Pathophysiology of Diabetes mellitus

The cause of diabetes mellitus in dogs and cats may differ but the pathophysiology remains the same:

  • An absolute or relative insulin deficiency
  • Reduced tissue utilization of glucose
  • Extracellular hyperglycaemia and intracellular hypoglycaemia

The consequences of extracellular hyperglycaemia and intracellular hypoglycaemia are shown in the diagram. Please click the thumbnail to enlarge.

pathophysiology of diabetes mellitus

Pathophysiology of Diabetes Mellitus