Pharmacokinetics of Caninsulin
Caninsulin is an aqueous suspension of 40 IU highly purified porcine insulin per ml, consisting of 30% amorphous and 70% crystalline zinc insulin.
In dogs the amorphous fraction has peak activity approximately 3 hours after subcutaneous administration and the effects last for about 8 hours. Thereafter, the effect is maintained by the crystalline fraction, which has a slower onset of action and peak effects from 7 to 12 hours following injection. Afterwards, the effect gradually declines to zero.
In cats, the total duration of action is around 12 hours.
Pharmacokinetics in dogs Click on icon for full image: | Pharmacokinetics in Cats Click on icon for full image: |
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