Initial Insulin Dosage for Diabetic Cats

Calculation of Initial Caninsulin Dosage for Diabetic Cats

The dose of Caninsulin and the interval between injections has to be tailored to suit each individual diabetic cat. All cats should be weighed accurately before commencing treatment (and at follow up visits).

Hypoglycaemia

As hypoglycaemia is a major concern and to be avoided at all costs

  • The animal's body weight should be rounded down to the nearest whole kilogram
  • The calculated dose of insulin rounded down to the nearest whole unit

This helps to avoid overdosing particularly during initial stabilisation.

Insulin dosage for diabetic cats

Starting dose:

  • 0.25-0.5 IU/kg body weight twice daily.

Pre-treatment blood glucose concentration is used as guidance for the calculation of initial insulin dose in cats. See table below:

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Baseline blood glucose concentration

(mmol/l)

Baseline blood glucose concentration

(mg/dl)

Initial Caninsulin dose (rounded down to the nearest whole unit)
<20 mmol/l
<360 mg/dl
0.25 U/kg body weight
>20 mmol/l
>360 mg/dl
0.5 U/kg body weight

Remember to round the cat’s bodyweight downto the nearest whole kilogram and the calculated dose downto the nearest whole unit.

Avoid unduly high starting doses in cats, especially in overweight cats, where the ideal bodyweight should be used. The maximal dose should not exceed 2 IU per cat twice daily in the first 2-3 weeks of treatment.

Subsequent dose adjustments should be in increments of 1IU per injection. For more information see dose adjustment.